Which designer is known for influencing the aesthetic beauty in interiors through her work for wealthy clients?

Elsie de Wolfe is celebrated for her pioneering role in shaping the aesthetic beauty of interior spaces, particularly for affluent clientele in the early 20th century. She is widely recognized as one of the first professional interior designers and played a significant part in elevating the practice of interior design from domestic decoration to a recognized profession.

De Wolfe emphasized creating elegant and sophisticated spaces that exuded comfort and style, often favoring a light, airy aesthetic that incorporated a blend of traditional and modern elements. Her work for wealthy clients, including socialites and prominent figures of her time, helped to popularize her vision of designing interiors that were not only beautiful but also functional and reflective of the clients' personalities and lifestyles.

This ability to merge aesthetic appeal with practicality set a new standard in interior design, influencing generations of designers who followed. The other designers listed, while also influential in their own rights, did not focus specifically on the same combination of wealthy clientele and aesthetic impact in the same manner as Elsie de Wolfe, making her the most accurate choice for this question.